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pentobarbital decreases levels of toremifene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers maximize rate of toremifene metabolism, reducing the regular-condition focus in serum.pentobarbital will minimize the extent or result of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metaboli